Will 59-250 work in aluminum screens?

It depends on the screen frame. Andersen used the 59-250 in screens made before 1991. After 1991, however, Andersen went to the thicker 59-270 spline. You need to measure up the spline or the groove in the screen to make sure your are ordering the correct size. Foam spline is easy to work with because it is more forgiving than the older vinyl. The foam squeezes into the screen groove then expands to hold in the screen mesh.

I your screen was made in 1991, then yes I would recommend the 59-270.